Connect with us

Hacking Matter

Doctors Have Successfully 3D Printed A Knee Meniscus

Published

on

Recently, doctors at Columbia University Medical Center have been able to merge 3D printing and the power of MRIs to create a scaffold of a knee meniscus. They can make a replica of the meniscus from 3D MRI images and print a new one.  This breakthrough, already tested successfully in sheep, could revolutionize the way joints and ligaments are treated when damaged or worn.

Project leader Jeremy Mao said:

This accomplishment is a first as the scaffold is infused with two recombinant human proteins: connective growth factor (CTGF) and transforming growth factor β3 (TGFβ3). Dr. Mao and his team found that the sequential delivery of these two proteins attracts existing stem cells from the body and induces them to form meniscal tissue.

Torn and damaged meniscus is more prevalent in today’s society, as from younger ages people are playing more sports and staying active far longer than before. The wear and tear on a person’s body are often felt in the joints first. The meniscus is like a shock absorber in the knee between the femur and the tibia. The stress of many different things like sport or advancing age can cause tears or worn out meniscus which can cause pain and hasten arthritis. Frequently in sports injuries like this can end careers or at the very least cause a loss of performance.

Clinical Trials In Sheep

Tear of Medial Meniscus

Tear of Medial Meniscus

The first trials were done in sheep – the doctors were able to create the 3D subsumable printed meniscus which then treated with the proteins and implanted in the sheep were able to replace the damaged meniscus. The sheep was back to normal function in the affected joint in about six weeks.

Now, think of this from the point of view of an athlete, or someone who is older and become immobile due to an injury or wear and tear. It changes things and in a good way for both. Right now, there are few things that can be done for a torn meniscus. They can, sometimes, stitch small tears or remove it completely, or have tissue from other parts of their body harvested, shaped and implanted. This procedure also can be done with tissue harvested from cadavers. These risky procedures have a low success rate and adverse side effects such as rejection and separation can occur.

If the trials that they are seeking further funding for go well, people will have a viable way to be able to recover from injuries to the meniscus. Successful trials can open the door for treating other joint and ligament damage. Older folks who are suffering from wear and tear can get mobility and quality of life back. Athletes can have a chance at reversing career ending injuries. The fact that, so far, the trials have been able to do this without stem cell treatments, and instead prompting the body to rebuild the meniscus on its own is also an accomplishment. While many advances are being made in stem cell therapies, getting the body to repair itself lessens the steps involved and risks.

Dr. Mao said:

We envision that personalized meniscus scaffolds, from initial MRI to 3D printing, could be completed within days,” said Dr. Mao. The personalized scaffolds will then be shipped to clinics and hospitals within a week.

There are over 1 million surgeries on meniscus tears each year in the US alone. This procedure should lower the rate by reducing the number of knees that end up requiring multiple surgeries, and it does open the door to living a more active life as we age. Columbia University Medical Center researchers headed up by Dr. Jeremy Mao are confident that this procedure will be a success in humans, and are currently getting funding in place to move to the clinical trial.

The world of medical science is starting to intersect yet again with science fiction in new ways. What is coming next is both exciting, and the limits are being stretched every day what we can do.

The full paper on the procedure is available on Science Transitional Medicine.

What do you think about the 3D printed meniscus treatment, is it a good breakthrough or is it taking us down the rabbit hole that may not end up with the desired results?

Images from Wikimedia Commons and Columbia University Medical Center.

Important: Never invest (trade with) money you can't afford to comfortably lose. Always do your own research and due diligence before placing a trade. Read our Terms & Conditions here. Trade recommendations and analysis are written by our analysts which might have different opinions. Read my 6 Golden Steps to Financial Freedom here. Best regards, Jonas Borchgrevink.

Rate this post:

Important for improving the service. Please add a comment in the comment field below explaining what you rated and why you gave it that rate. Failed Trade Recommendations should not be rated as that is considered a failure either way.
0 votes, average: 0.00 out of 50 votes, average: 0.00 out of 50 votes, average: 0.00 out of 50 votes, average: 0.00 out of 50 votes, average: 0.00 out of 5 (0 votes, average: 0.00 out of 5)
You need to be a registered member to rate this.
Loading...

Giulio Prisco is a freelance writer specialized in science, technology, business and future studies.




Feedback or Requests?

Altcoins

Crypto Market Development: South Korea’s National Policy Committee Chair Calls For ICO Legalization

Published

on

  • A member of South Korea’s governing Democratic party and the chairman of Korea’s National Policy Committee, Min Byung-Doo, is urging to ease the current regulations on Initial Coin Offerings (ICOs).
  • Min Byung-Doo wants to introduce necessary regulatory framework, allowing ICOs in the country.

Allow ICOs In South Korea

The South Korean National Policy Committee Chief, Min Byung-Doo, is calling for a regulatory framework to be explored. This would be to allow for Initial Coin Offerings (ICOs) to take place within the country. He stated that the current prohibiting of ICOs weakens the industry’s competitiveness appeal with foreign markets. Further boldly adding, this would be preventing growth.

In his statement at to lawmakers, Byung-Doo said, “We can see that the flow of investment is clearly changing compared to ICO and angel fundraising. The ICO has raised $1.7 billion for Telegram and $4 billion for Block.One, it is getting bigger and bigger.”

Further in the statement, Min Byung-Doo said, “Let the government, the National Assembly and the blockchain association quickly create a working group to block fraud, speculation, money laundering and develop the block-chain industry,”. However, he acknowledged the government’s reluctance to create the needed framework.

In September 2017, the Financial Services Commission in South Korea announced a ban on ICOs. The law has not yet been enacted.

Crypto Market Reaction

A lack of reaction has been observed for now, despite this determination to help further legitimize the digital currency market in South Korea. Crypto market developments in the country are always watched very carefully. This is given their large crypto market participation. It was reported in December 2017 that South Korea accounted for as much as 17% of all Ethereum trades occurring in cryptocurrency markets.

Market Reactions To South Korean Related News

Ripple (XRP) crashed in January, following CoinMarketCap’s decision to remove XRP price data from Korean exchange desks. This as a result largely brought down the total average.

XRP/USD Coinmarketcap update triggered drop

On 11th January, Korean crypto exchange Coinrail was hacked, and over $40 million in tokens were stolen. Bitcoin initially dropped over 11% on this.

BTC/USD Coinrail hack triggered drop

One final example, UPbit, a South Korean exchange, was investigated by authorities for illicitly moving customer funds to the account of its executives. Bitcoin initially dropped over 7% on the news.

BTC/USD UPbit investigation triggered drop

Given the above mentioned, one should keep an eye on any developments coming out of South Korea, for the foreseeable future.

Disclaimer: The author owns bitcoin, Ethereum and other cryptocurrencies. He holds investment positions in the coins, but does not engage in short-term or day-trading.

Featured image courtesy of Shutterstock.

Important: Never invest (trade with) money you can't afford to comfortably lose. Always do your own research and due diligence before placing a trade. Read our Terms & Conditions here. Trade recommendations and analysis are written by our analysts which might have different opinions. Read my 6 Golden Steps to Financial Freedom here. Best regards, Jonas Borchgrevink.

Rate this post:

Important for improving the service. Please add a comment in the comment field below explaining what you rated and why you gave it that rate. Failed Trade Recommendations should not be rated as that is considered a failure either way.
1 vote, average: 5.00 out of 51 vote, average: 5.00 out of 51 vote, average: 5.00 out of 51 vote, average: 5.00 out of 51 vote, average: 5.00 out of 5 (1 votes, average: 5.00 out of 5)
You need to be a registered member to rate this.
Loading...

4.5 stars on average, based on 32 rated postsKen has over 8 years exposure to the financial markets. During a large part of his career, he worked as an analyst, covering a variety of asset classes; forex, fixed income, commodities, equities and cryptocurrencies. Ken has gone on to become a regular contributor across several large news and analysis outlets.




Feedback or Requests?

Continue Reading

Altcoins

Crypto Market Update: Japan’s Self-Regulatory Group (JVCEA) Readying Tighter Rules on Digital Assets

Published

on

  • A group of cryptocurrency exchange operators in Japan is readying to tighten up measures following recent cyber breach.
  • Action follows reported hack earlier in the month; cryptocurrency exchange Zaif lost an estimated $59.67 million.

Self-Regulatory Group Set To Tighten Rules

The Japan Virtual Currency Exchange Association (JVCEA) is exploring new rules to safeguard against cyber theft, including setting a cap on the amount of digital currencies managed online. This is citing informed sources, being reported by local news outlet, the Japan Times.

Informed sources detailed that the cap will likely to be around 10 – 20% of customer deposits. The JVCEA are said to be soon revising its rules, which were originally drawn up in June following multiple cyber attacks. These will be implemented once all has been approved by the Financial Services Agency. This is as part of the payment services law process in the country.

The move likely received large motive due to the reported hack earlier in September. The Japanese start-up Tech Bureau said that its cryptocurrency exchange, known as Zaif, had been hacked. Losses were estimated around $59.67 million of Bitcoin and two other digital currencies -Bitcoin Cash and Monacoin.

Market Reaction

No initial reaction was observed across the cryptocurrency market on this latest update, coming out of Japan as of Sunday 30th September. Despite this, however, Japan and crypto sell-off are not uncommon to have been used in the same sentence over the past years and even months. This means volatility could be in store for digital assets in the short term.

Back in January of this year, the largest reported hack on a Japanese exchange took place with Coincheck losing $530 million worth of NEM in a coordinated attack. This incident massively spooked the market, and was  a heavy contributor to the large sell-off in January. As we’ve observed over the past eight months, the market has yet to reclaim January’s peak (although this can’t be solely attributed to the theft). At the time, South Korea’s Attorney General had already spooked investors with FUD related to the possible banning of digital currencies in the country.

Against this backdrop, investors are advised to pay attention to Japan-related volatility.

BTC/USD weekly chart

Most recently, looking in the month of June, another sell-off was seen. This one came after Japan’s financial regulator ordered several cryptocurrency exchanges to improve their practices against money laundering. The action led bitFlyer — the country’s largest crypto exchange — to suspend new account creation. This was initiated to improve internal processes in order to curb money laundering and terrorist financing.

Disclaimer: The author owns bitcoin, Ethereum and other cryptocurrencies. He holds investment positions in the coins, but does not engage in short-term or day-trading.

Featured image courtesy of Shutterstock.

Important: Never invest (trade with) money you can't afford to comfortably lose. Always do your own research and due diligence before placing a trade. Read our Terms & Conditions here. Trade recommendations and analysis are written by our analysts which might have different opinions. Read my 6 Golden Steps to Financial Freedom here. Best regards, Jonas Borchgrevink.

Rate this post:

Important for improving the service. Please add a comment in the comment field below explaining what you rated and why you gave it that rate. Failed Trade Recommendations should not be rated as that is considered a failure either way.
1 vote, average: 5.00 out of 51 vote, average: 5.00 out of 51 vote, average: 5.00 out of 51 vote, average: 5.00 out of 51 vote, average: 5.00 out of 5 (1 votes, average: 5.00 out of 5)
You need to be a registered member to rate this.
Loading...

4.5 stars on average, based on 32 rated postsKen has over 8 years exposure to the financial markets. During a large part of his career, he worked as an analyst, covering a variety of asset classes; forex, fixed income, commodities, equities and cryptocurrencies. Ken has gone on to become a regular contributor across several large news and analysis outlets.




Feedback or Requests?

Continue Reading

Hacking Matter

The 2016 Nobel Prize in Chemistry Vindicates Radical Visions of Molecular Nanotechnology

Published

on

The Nobel Prize in Chemistry 2016 was awarded jointly to Jean-Pierre Sauvage, Sir J. Fraser Stoddart and Bernard L. Feringa “for the design and synthesis of molecular machines.” The award vindicates the dreams of nanotechnology enthusiasts, and points the way to the molecular nanotechnology proposed by Drexler in the eighties.

(more…)

Important: Never invest (trade with) money you can't afford to comfortably lose. Always do your own research and due diligence before placing a trade. Read our Terms & Conditions here. Trade recommendations and analysis are written by our analysts which might have different opinions. Read my 6 Golden Steps to Financial Freedom here. Best regards, Jonas Borchgrevink.

Rate this post:

Important for improving the service. Please add a comment in the comment field below explaining what you rated and why you gave it that rate. Failed Trade Recommendations should not be rated as that is considered a failure either way.
0 votes, average: 0.00 out of 50 votes, average: 0.00 out of 50 votes, average: 0.00 out of 50 votes, average: 0.00 out of 50 votes, average: 0.00 out of 5 (0 votes, average: 0.00 out of 5)
You need to be a registered member to rate this.
Loading...

Giulio Prisco is a freelance writer specialized in science, technology, business and future studies.




Feedback or Requests?

Continue Reading

Recent Comments

Recent Posts

A part of CCN

Hacked.com is Neutral and Unbiased

Hacked.com and its team members have pledged to reject any form of advertisement or sponsorships from 3rd parties. We will always be neutral and we strive towards a fully unbiased view on all topics. Whenever an author has a conflicting interest, that should be clearly stated in the post itself with a disclaimer. If you suspect that one of our team members are biased, please notify me immediately at jonas.borchgrevink(at)hacked.com.

Trending